Fourteen matches, then a four-month gap
The sixth season was meant to confirm what the fifth had established. It began at the National Stadium in Karachi on 20 February with every match scheduled in Pakistan. On 4 March, with fourteen of the thirty group matches played, the board suspended it. Positive COVID-19 tests had appeared across several squads inside the tournament's bio-secure arrangements, which were not secure.
The board first proposed finishing the season in Karachi in June. On 4 May all six franchises asked for the remainder to be moved abroad as case numbers rose in Pakistan. Approval to play in Abu Dhabi came on 20 May, and the tournament restarted at the Sheikh Zayed Stadium on 9 June. Sixteen group matches and the four playoff matches were played there in a fortnight, in front of almost nobody: the reported attendance for the season, 143,854, was the lowest for any completed edition, and most of it came from the Karachi leg.
Multan's month
Islamabad United won eight of their ten group matches and finished top. Multan Sultans, who had won two of their first four in Karachi, took second place with five wins. Sohaib Maqsood, who had been in and out of the Pakistan side for a decade, made 428 runs and was named player of the tournament. Shahnawaz Dahani, a fast bowler from Larkana in his first professional season, took 20 wickets, more than anyone. Babar Azam made 554 runs for Karachi Kings, the highest aggregate of the season, and Karachi still went out in the first playoff match.
In the Qualifier, Multan made 180 for 5 and bowled Islamabad United out for 149. Peshawar Zalmi beat Karachi by five wickets in Eliminator 1, Hazratullah Zazai taking the award, and then beat Islamabad by eight wickets in Eliminator 2 with 19 balls to spare, Zazai taking it again.
Abu Dhabi, 24 June
Multan batted first in the final and made 206 for 4, at that stage the highest total in a final of the competition. Peshawar were 159 for 9 at the end of their twenty overs. Sohaib Maqsood took the match award to go with the tournament award, and Multan Sultans, a franchise whose original ownership had been terminated three years earlier, won the title in their fourth season.
Two centuries were made in the season, Usman Khawaja's 105 for Islamabad and Sharjeel Khan's 105 for Karachi. Rashid Khan's 5 for 20 was the best bowling. The competition had by then been staged at home, abroad, and both at once, and 2022 would be the first season since 2020 to be completed in a single country without interruption.